ADLER PHENOL OXIDATION
 | |
ADLER PHENOL OXIDATION DISCONNECTION |
 | |
ADLER PHENOL OXIDATION MECHANISM |
 | |
ADLER PHENOL OXIDATION REACTION |
NOTES :
Sodium periodate reacts very slowly with unsubstituted phenols, however when alkyl substituents are present on the phenol the periodate is rapidly consumed and the phenolic hydroxyl is oxidised. See also Teuber reaction.
AHMED – STRONG SYNTHESIS
 |
| AHMED – STRONG DISCONNECTION |
 |
AHMED – STRONG SYNTHESIS |
 |
AHMED – STRONG SYNTHESIS |
NOTES :
Alkyl acetylenes react in the presence of sodamide with chloro iodo alkanes to form acetylenic chlorides. These in turn, via the nitrile or Grignard reagent, and with subsequent selective hydrogenation of the triple bond in the presence of Raney nickel are converted into mono-unsaturated fatty acids. (cis-form). See also Raphael synthesis.